Mar 29

On a bad day, the pain scientists can feel bogged down, the researcher’s equivalent of writer’s block. That is why we include some of the material here on plants. Strange as it sounds, the cure for central pain just might come from one of these weirdo plant chemicals.

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Mar 28

A little work coming out on phosphatases is interesting.

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Mar 27

Hypericum reflexum L. fil. is a plant found in the Canary Islands. H. Reflexum is related to Hypericum canariense, H. glandulosum, and H. grandifolium (Hypericaceae) which are Mycorrhizae plants from the Canaries.

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Mar 24

The course of true medicine never runs smooth. We lament those who developed Central Pain as a result of attempting to walk again, however haltingly, from stem cell implants.

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Mar 22

This is too hot to handle, but too common a lament to ignore. Those who ought to support you have the potential to deliver the most crushing blows. Et tu Brute?* Keep your theology away from our pain. Keep your social commentary off our dysesthesia. It is an injury, for heaven’s sake, not a statement about our worthiness. If you cannot help the suffering, leave them alone.

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Mar 21

Ready or ready, here they come! The new oral N type calcium channel blockers. Merck appears to be the flagbearer and we can only hope they have fierce competitors nipping at their heels. This venture represents a brave step for Merck after their recent pounding over Vioxx. We are so grateful they have not given up on pain research. Go Merck!

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Mar 19

Humans tend to think in terms of that for which they have a frame of reference. There is no frame of reference for severe pain unrelated to a flesh injury, for an injury induced chemical/genetic defect in the nerve itself. Therefore, central pain is unthinkable.

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Mar 17

It appears that not only the lowly sea snail (ziconotide) but also the cobra produces a venom which is a potent neurotoxin, but an analgesic as well.

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Mar 14

Daydreaming. If you can dream it, you can dream it.

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Mar 13

It looks like BDNF is one growth factor which runs uphill.

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